Mobile Suit Gundam GQuuuuuuX (Japanese: 機動戦士Gundam GQuuuuuuX, Hepburn: Kidō Senshi Gandamu Jīkuakusu) is a Japanese anime television series jointly produced by Studio Khara and Sunrise. It is the sixteenth mainline installment of the Gundam franchise, the first full series to be set in the Universal Century calendar since Mobile Suit Victory Gundam (although set in an alternate timeline), the second television series to be aired during Japan's Reiwa era, and the second in a row after The Witch from Mercury to feature a female lead.

A compilation film was released by Toho and Bandai Namco Filmworks in January 2025, while the TV series itself aired shortly thereafter from April to June of the same year. The TV series is the shortest in the franchise's history by episode count (excluding OVAs), having a total of 12 episodes.

In UC 0085, five years after the Principality of Zeon won the One Year War, Amate Yuzuriha, a high school student living in the Side 6 space colony Izuma, crosses paths with Nyaan, a war refugee. Her encounter with Nyaan leads her to get involved in an incident when both the Principality of Zeon and the Space Police are pursuing the missing Red Gundam after it suddenly re-emerges. To catch the Red Gundam, Zeon sends out Xavier Olivette in the gMS-Ω GQuuuuuuX, a prototype Gundam meant for Newtype pilots. However, while trying to capture the Red Gundam, Xavier crashes into the space colony and is ejected from the GQuuuuuuX. Amate jumps into the cockpit of the GQuuuuuuX, steals it, and subsequently defeats the Police Force, allowing the Red Gundam to escape. The GQuuuuuuX is taken by the Pomeranians, an underground team of mechanics participating in Clan Battles, a series of illegal and high-stakes mobile suit dueling matches. After meeting the Red Gundam's pilot, Shuji, Amate chooses to join him in Clan Battles with the Pomeranians, fighting alongside him in the GQuuuuuuX.