Monika is noted by the other characters to be smart, beautiful, confident and athletic. She's not as talkative as the other girls, but this is implied to not be through choice.

Monika had previously been a part of the Debate Club but left due to all the inner politics and drama, highlighting a desire for order, freedom of topic and friendliness. The Literature Club, which she founded after leaving the Debate Club, is very important to Monika. She aspires for it to be a place to showcase and grow everyone's passion for literature. Monika openly displays care and concern for her club mates, praising each member's writing style and even comparing them to famous authors and poets.

Natsuki is a brash, blunt, seemingly arrogant girl with a cute, softer interior as a result of insecurity. While she is impulsive and can speak without thinking, Natsuki truly cares about her friends and, even when she has obvious anger issues, doesn't enjoy fights or arguments with people. Over the course of the game, we see that she worries about Yuri and on one occasion, gives the protagonist a note asking him to help Yuri, fearing that if she spoke out then it would cause more arguments.

Her cute interior also involves a love of manga, particularly those in the slice-of-life genre, and baking. She has been known to store her manga collection in the Literature Club out of embarrassment, and while the rest of the club obviously knows about her interest, she is still hesitant to talk about it. Natsuki also likes cute things, like cupcakes with cat faces. She also likes poems with cuter, happier words, though her own poems are still about sad things, such as being persecuted for your hobbies. Her simplistic writing style puts her at odds with Yuri.

Natsuki dislikes being called "cute," even when she acts as such, or does cute things, and will deny any claims from others relating to this, nevertheless she is much more comfortable exposing her sweet side once she knows people aren't going to tease her about it. Natsuki hates it if she isn't taken seriously, whether it's her writing, her hobbies, or just her overall demeanor. It is likely Natsuki learned to be ashamed of herself and her hobbies, because her classmates judge her and her implied abusive father, making her abrasive nature a coping mechanism. This is also implied in her secret poem "Things I Like About Papa."

Yuri is portrayed throughout the majority of the game as being shy, generous, polite, passionate about topics she is interested in, apologetic, very intelligent, mature, and eloquent. Despite her maturity, Yuri does argue with Natsuki over their differing opinions on writing styles. While she tries to avoid the conflict at first, Yuri can be very passionate and stubborn, with her outright cursing in Act 2, though this is most likely be due to Monika's tampering. Yuri can be innocently insensitive, as she sometimes comes across as condescending or pretentious without truly meaning to. Once she realizes what she said could be considered insensitive, she almost immediately apologizes, repeatedly saying she didn't mean it.

Yuri is the "shrinking violet" (a term to describe a character who prefers to blend in with the scenery than to attract unwanted attention) of the club members because of her constant apologetic nature and shyness to discussions beyond her category of interest, her interests being literature, horror, and general surrealism, which she examines and articulates expertly and encourages others to follow as well. Yuri prefers poetry that uses metaphorical symbolism and enjoys collecting unusual ornate knives, which she uses to cut herself, not because of depression, but because it makes her feel euphoric.

Sayori is portrayed as a talkative person, being very cheerful and kind and the archetype of a Genki Girl. She is very clumsy and notorious for finding ways to accidentally hurt herself or to drop things, as well as tricking people just to get food. She is usually the only character, other than the protagonist, capable of breaking up arguments, and she is described as being paramount to keeping a relaxing atmosphere in the Literature Club, which becomes even more apparent after her suicide. Monika notes that while she may look like a good leader, Sayori is usually better when it comes to dealing with people. Sayori tries her best to help everyone be happy and dislikes attention directed at her well-being because she feels unworthy of anything that others have to offer her.

Sayori's depression makes her disorganized, and she often "cannot find a reason to get out of bed in the morning"; her room is untidy, and we are told the protagonist often used to clean her room for her. The protagonist notes how there hasn't been much change in her, and the changes the protagonist notices in her later are due to Monika's interference, amplifying her depression and suicidal tendencies. Her relationship with the protagonist and other people's happiness are her main coping mechanisms since she believes that if she makes everyone else happy, she will not have a reason whatsoever to be unhappy.